On the Effects of the Gene a on the Chemical Composition of Ephestia KUhniella Zeller.
نویسنده
چکیده
H E gene a in the flour moth Ephestia kuhniella is an eye color mutantT that is, its most obvious phenotypic effect consists in a reduction of the size and number of the pigment granules in the eyes. Pigmentation in other parts of the body is also reduced. Color mutants constitute a group of genes most appropriate for phenogenetic studies, since they seem to be relatively easily accessible to investigation with chemical methods. In the case of the gene a, the affected pigments have been characterized chemically by BECKER (1939, 1942) and distinguished under the name “ommochromes” from the melanin pigments contained in the exoskeleton. It has been shown by injection experiments that these pigments are dependent for their development on the presence of kynurenin (BUTENANDT, WEIDEL, and BECKER 1g4oa) and that this substance is apparently missing in aa individuals. Kynurenin seems to act as a precursor for the ommochrome pigments (BECKER 1939: KIKKAWA 1941; KUHN and BECKER 1942). The action of the gene a on pigment characters is therefore due to the fact that the precursor kynurenin is not formed. From chemical considerations as well as from comparison with mammals (KOTAKE and collaborators) it is generally accepted that kynurenin is ordinarily formed by oxidation of tryptophane in a series of reactions: ,rJ CHz-CH(NHz)-COOH CHzCH (NHz)-COOH
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ورودعنوان ژورنال:
- Genetics
دوره 31 5 شماره
صفحات -
تاریخ انتشار 1946